Mental Stress and Heart Disease

It is well established that emotional stress, anger, depressed mood and other psychological states can trigger acute myocardial infarction and sudden cardiac death in susceptible individuals. 

In one NIH-funded study, ECCRI researchers are attempting to clarify the pathophysiology of mental stress ischemia (MSI) and its prognosis.  A multidisciplinary team of scientists is examining the brain, vascular, genetic, hormonal, and behavioral correlates of MSI and their influence on future cardiac events.